Introduction to PET Physics

1. Introduction

2. The physical principles of PET

2.1 Introduction
2.2 Positron emission and annihilation
2.3 Coincidence detection and electronic collimation
2.4 Photon interactions in human tissue and correction for gamma-ray attenuation
2.5 Types of coincidence events

3. 2D mode and 3D mode

3.1 Principles of operation
3.2 Sensitivity to true coincidence events
3.3 Sensitivity to scattered events
3.4 Sensitivity to random events
3.5 Effect of camera geometry

4. Image reconstruction

4.1 Introduction
4.2 Notation and mathematical theorems used
4.3 Analytic image formation in 2D PET
4.4 Filtered Back-Projection in 3D and 3D-RP

5. Detection systems in PET

5.1 Introduction
5.2 Scintillators and scintillation detectors
5.3 Pulse processing
5.4 Coincidence processing
5.5 Dead-time
5.6 Block detectors
5.7 Camera configurations in PET

6. Corrections for quantitative PET in 2D and 3D mode

6.1 Introduction
6.2 Attenuation correction
6.3 Correction for random coincidences
6.4 Scatter correction
6.5 Detector normalisation
6.6 Dead-time correction

References