2008-09 Seminars
Iron oxide nanoparticles for brain cancer imaging
Chen Fang, Graduate Student and Research Assistant in UW's Materials Science and Engineering Labs, will be the featured speaker. Materials Science and Engineer has 3 labs that develop materials and devices for biological and medical applications.
Practice
We will use our group meeting time for practice presentations for the upcoming Society of Nuclear Medicine Annual Conference.
Breast Cancer Imaging and Other Projects
David Mankoff, M.D. will be the featured speaker. Dr. Mankoff is an Associate Professor in the UW School of Medicine Radiology Department, and a practicing physician at Seattle Cancer Care Alliance (SCCA). He specializes in thyroid cancer treatment, and uses state-of-the-art imaging to better diagnose cancer and guide treatment.
Adoptive T cell therapy for HER2-positive breast cancer: Successes and obstacles
Vy Lai, a Senior Fellow in the Center for Translational Medicine in Women's Health, will be our featured speaker. Dr. Lai is a member of Dr. Nora Disis's Tumor Vaccine Group, which is a multidisciplinary group of investigators focused on the diagnosis, prevention and treatment of cancer with novel, immune-based therapies. http://depts.washington.edu/tumorvac All are welcome.
cAMP Signaling in Brown Adipose Tissue: Roles for Phosphodiesterase 8A
Steve Kraynik from the department of Pharmacology will be the guest speaker.
Journal Club: Comparison of organ residence time estimation methods for radioimmunotherapy dosimetry and treatment planning - patient studies
The estimation of organ residence time is essential for high-dose myeloablative regimens in radioimmunotherapy (RIT). Frequently, this estimation is based on a series of simple planar scans and planar processing. The authors previously performed a simulation study which demonstrated that the accuracy of this methodology is limited compared to a hybrid planar/SPECT residence time estimation method. In this work the authors applied this hybrid method to data from a clinical trial of high-dose myeloablative yttrium-90 ibritumomab tiuxetan therapy.
Controlling Image Quality in Iterative PET Image Reconstruction
Richard M Leahy, Professor, Electrical Engineering and Radiology at University of Southern California, will describe a model-based approach that his group developed over the last several years. This approach combines resolution recovery with optimized noise handling with the goal of producing images whose resolution properties are independent of source activity and distribution and can be explicitly controlled through a single resolution parameter.
UW Travel
Radiology Department Grants and Contracts staff will discuss the new Time Off/Travel Request plus outline travel expenses and reimbursements
Motion-compensated image reconstruction
Image reconstruction of moving objects (such as breathing patients) is challenging due to inconsistencies between measurements acquired at different phases of the motion. Compensating for motion during image reconstruction requires tools similar to those used in nonrigid image registration. In the first part of this talk Dr. Jeffrey Fessler will discuss an approach for nonrigid image registration based on B-spline deformation models. The key feature of this approach is that it provides a simple way to ensure that the estimated deformation is invertible (diffeomorphic). This constraint is important for the registration to be physically plausible. In the second part of the talk a couple of different approaches for using this type of image registration tool in the context of image reconstruction of moving objects will be discussed.
Journal Club: New PET Scanner with Semiconductor Detectors
A New PET Scanner with Semiconductor Detectors Enables Better Identification of Intratumoral Inhomogeneity by Tohru Shiga, et. al.
High-Resolution Rectangular dMiCE Breast PET Scanner
Kyle Champley, IRL graduate student, will be the presenter in preparation for his General Exam
Note the day change
David Lewis, M.D., UW Professor Radiology, will present soon-to-be published results of a brain trauma study using SPECT imaging.
Quantitative FET PET in patients with resected glioblastoma
Frank Thiele, UW Radiology Visiting Scientist, Senior Member Research Staff, Philips Research North America will be the presenter
Segmentation Review
Serena Fabbri, Ph.D., will review the segmentation work she is doing to derive attenuation-correction images for PET from MR images. This work has raised many questions so the meeting will be a discussion format focused on these questions.
Spectral x-ray technology
The paper, "Multienergy photon-counting K-edge imaging," reports on a prototype multi-energy photon-counting x-ray CT scanner. We'll hear about application of this technology.
SPIE Medical Imaging Conference
NEW TIME Adam Alessio will lead the discussion of the interesting work he saw last week at the SPIE Medical Imaging Conference
On Holiday
The Imaging Research Laboratory seminar will take a break this week and return on Feb. 19, 2009. Happy Presidents Day.
