Technical Developments

Technical Developments and Methodological Considerations



  • AkiyamaLF, RichardsTR, Imada T, Dager SR, Wroblewski L, Kuhl PK. Age-Specific Average Head Template for Typically Developing 6-Month-Old Infants. PLOS One 2013; 8(9): e73821. Published online September 12, 2013.
  • Farzinfar M, Oguz I, Smith RG, Verde AR, Dietrich C, Gupta A, Escolar ML, Piven J, Pujol S, Vachet C, Gouttard S, Gerig G, Dager S, McKinstry RC, Paterson S, Evans AC; The IBIS network. Diffusion Imaging Quality Control via Entropy of Principal Direction Distribution. Neuroimage. 2013 May 16. doi:pii: S1053-8119(13)00516-8. 10.1016/j.neuroimage. 82:1-12, 2013. Epub 2013 May 17. PMID: 23684874
  • Posse S, Otazo R, Dager SR, Alger J. Magnetic Resonance Spectroscopic Imaging: Principles and Recent Advances.  J Magn Reson Imaging. 37(6):1301-25, 2013. Epub 2012 Nov 27 PMID: 23188775
  • Prescot AP, Richards T, Dager SR, Choi C, Renshaw PF: Phase-adjusted echo time (PATE)-averaging 1 H MRS: application for improved glutamine quantification at 2.89T. NMR Biomed. 2012 Nov;25(11):1245-52. doi: 10.1002/nbm.2795. Epub 2012 Mar 12. PMID: 22407923 [PubMed - in process]
  • Kim SH, Fonov V, Dietrich C, Vachet C, Hazlett HC, Smith R, Graves MM, Piven J, Gilmore JH, Dager SR, McKinstry R, Paterson S, Evans AC, Collins LD, Gerig G, Styner M. Adaptive prior probability and spatial temporal intensity change estimation for segmentation of the one-year-old human brain. J Neurosci Methods 212(1):43-55, 2013. PMID: 23032117
  • Posse S, Otazo R, Dager SR, Alger J: MR spectroscopic imaging: Principles and recent advances.  J Magn Reson Imaging. 2012 Nov 27. doi: 10.1002/jmri.23945. [Epub ahead of print] PMID: 23188775
  • Kim JE, Lyoo IK, Estes AM, Renshaw PF, Shaw DW, Friedman SD, Kim DJ, Yoon SJ, Hwang J, Dager SR. Laterobasal Amygdalar Enlargement in 6- to 7-Year-Old Children with Autism Spectrum Disorder. Archives of General Psychiatry. 67(11):1187-97, 2010 PMID: 21041620
  • Corrigan, NM, Richards TL, Friedman SD, Petropoulos H, Dager SR. Improving 1H MRSI measurement of cerebral lactate for clinical applications. Psychiatry Res. 182(1):40-47, 2010.
  • Dager SR, Corrigan NM, Richards TL, Posse S. Research Applications of Magnetic Resonance Spectroscopy (MRS) to Investigate Psychiatric Disorders. Topics in Magnetic Resonance Imaging. 19(2):81-96, 2008. PMID: 19363431
  • Giardino ND, Friedman S, Dager SR: Every Breath You Take: Anxiety and Its Implications for Functional Brain Imaging. Compr Psychiatry. 48(2):103-112; 2007.
  • Serafini S, Steury K, Richards TR, Corina D, Dager SR, Abbott R, Berninger V: Comparison of fMRI and PEPSI During Language Processing in Children.  Mag Reson Med 45:217-225, 2001.

  • Strauss WL, Dager SR: Magnetization Transfer of Fluoxetine in the Human Brain using 19 Fluorine Magnetic Resonance Spectroscopy.  Biol Psychiatry 49(9):790-802, 2001.

  • Strauss WL, Layton ME, Dager SR:  Characterization of Human Brain Pharmacokinetics Using A Two Compartment Model.  Biol Psychiatry 45:1384-1388, 1999.
  • Posse S, Wiese S, Gembris D, Mathiak K, Kessler C, Grosse-Ruyken ML, Elghawaghi B, Richards T, Dager SR, Kiselev VG:  Enhancement of BOLD-Contrast Sensitivity by Single-Shot Multi-Echo Functional MR Imaging.  Magn Reson Med 42:87-97, 1999.

  • Posse S, Wiese S, Kessler C, Gembris D, Weiss U, Peyerl M, Grosse-Ruyken ML, Elghawaghi B, Richards T, Dager S:  Functional MR Imaging of Visual and Olfactory Activation Using Quantitative  T2*-Mapping.  Neuroimage 7(4):57, 1998.

  • Posse S, Dager SR, Richards TL, Yuan C, Artru AA, Ogg R, Müller-Gärtner HW, Hayes C:  In Vivo Measurement of Regional Brain Metabolic Response to Hyperventilation Using Functional Proton Echo-Planar Spectroscopic Imaging (PEPSI).  Magn Reson Med 37:858-865, 1997.

  • Posse S, Olthoff U, Jäncke L, Weckesser M, Müller-Gärtner HW, Dager SR:  Regional Dynamic Signal Changes During Initiation of Controlled Hyperventilation Assessed by BOLD-Dependent fMRI.  Am J Neuroradiology 18:1763-1770, 1997.

  • Posse S, Müller-Gärtner HW, Dager SR:  Functional Magnetic Resonance Studies of Brain Activation.  Sem Clin Neuropsychiatry 1(1):76-88, 1996.

  • Dager SR, Swann AC:  Advances in Brain Metabolism Research:  Towards a Moving Picture of Neural Activity (editorial).  Biol Psychiatry 39:231-233, 1996.

  • Dager SR, Steen RG:  Applications of Magnetic Resonance Spectroscopy to the Investigation of Neuropsychiatric Disorders.  Neuropsychopharmacology 6(4)249-266, 1992.

Select Readings:

Research applications of magnetic resonance spectroscopy to investigate psychiatric disorders.

Anxiety respiration and cerebral blood flow implications for functional brain imaging.

Fluorine magnetic resonance spectroscopy measurement of brain fluvoxamine and fluoxetine in pediatric patients treated for pervasive developmental disorders.

MR spectroscopic imaging Principles and recent advances.

Phase-adjusted echo time (PATE)-averaging 1H MRS application for improved glutamine quantification at 2.89 T