Robert K. Doot, Ph.D.

Robert K. Doot, Ph.D.

  • Senior Fellow


Robert Doot graduated cum laude with a B.S. in Chemical Engineering from the University of Michigan.

I worked as a process engineer with Motorola and was awarded four United States patents in the field of integrated circuit (IC) packaging.

At the University of Washington I completed a M.S. in Bioengineering in 2005 with thesis titled Engineering two-dimensional networks of oriented microtubules for directed cargo transport. Then, I completed a dual Ph.D. in Bioengineering and Nanotechnology in 2008 with a dissertation titled Factors affecting quantitative PET as a measure of cancer response to therapy.


My research is focused on assessing the feasibility of using quantitative positron emission tomography (PET) as a response measure in multi-center clinical trials. This includes both measurement of the bias and variance of PET measures of long half-life phantoms at multiple sites and modeling of the impact of the range of PET measurement errors, the impact of PET analysis method (kinetic versus SUV), and impact of patient and tumor characteristics on study design for multi-center clinical trials employing PET measures.